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Gas-Liquid Chromatography

Definition: A variation of the gas chromatography process in which the chromatographic column is packed with a finely divided solid impregnated with a nonvolatile organic liquid. The sample to be analyzed is injected into the inlet of the column where it is quickly and completely vaporized. The gas stream carries it into the packed section, where the vapors contact the impregnated solids. The nonvolatile liquid phase tends to condense the vapors from the gas stream, and the moving gas phase tends to evaporate the condensed sample vapors. The vapors of each compound present in the sample in effect spend a characteristic fraction of time in the condensed phase, and the remainder in the mobile gas phase. Each chemical species will tend to migrate at its own characteristic rate and will be separated from other species by the time they emerge from the column. The detector senses the emergence of each sample component and provides an electrical signal to the recorder proportional to the concentration of each component in the emergent stream.

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