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Gel Permeation Chromatography
GPC


Definition: A column chromatography technique employing as the stationary phase a swollen gel made by polymerizing and cross-linking styrene in the presence of a diluent which is a nonsolvent for the styrene polymer.
Related Terms
Chromatography

The polymer to be analyzed is introduced at the top of the column and then is elutriated with a solvent. The polymer molecules diffuse through the gel at rates depending on their molecular size. As they emerge from the bottom of the column they are detected by a differential refractometer from which a molecular size distribution curve is plotted. See also CHROMATOGRAPHY.

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